Celleva Inc. · Innovating healing
One company, two platforms, one standard.
Different scientific objectives, product specifications, markets and regulatory environments call for different levels of biological complexity, molecular definition and process control. Running two platforms is what lets the manufacturing route be chosen against the application.
PEXT development is carried out in collaboration with the scientific team at Seoul National University, and production is operated in compliance with cGMP and cGLP standards.
Not every application requires the same product. Every application requires the same commitment to measurable quality.
- Headquarters
- Suite #506, 656 Gwonyuldae-ro, Deogyang-gu, Goyang-si, Gyeonggi-do, South Korea 10654
- Research collaboration
- Seoul National University, South Korea
- Manufacturing standards
- cGMP · cGLP
- Brand
- PEXT™ · Premium Exosomes Therapy
PEXT™
The name
PEXT stands for Premium Exosomes Therapy.
The mark is the ornament stamped on every vial. On this platform “premium” is not a grade of packaging. It is the claim that the producer cells were measured before anything was made from them, and that the measurements travel with the lot.
Scientific direction
Who stands behind the science
Prof. Dr. H. Eray Copcu, MD
Scientific Director
Plastic, Reconstructive and Aesthetic Surgery · Regenerative Medicine
Professor of Plastic, Reconstructive and Aesthetic Surgery, and the first academic in Turkey to establish a regenerative medicine department at a university.
Prof. Dr. H. Eray Copcu has worked on stromal-cell and regenerative treatment technologies since becoming a professor in 2011, across Turkey and Korea. He founded the aesthetic and plastic surgery departments at the medical faculties of both Adnan Menderes University and Izmir University, and went on to found the first regenerative medicine department in a Turkish university.
His research interests are cell therapy, stem cells and preadipocytes, alongside aesthetic and reconstructive breast surgery. He holds patents in stromal-cell transfer, and developed the MEST, ARAT and Supercharged MEST techniques now used internationally.
- Title
- Professor of Plastic, Reconstructive and Aesthetic Surgery
- Medical degree
- Ege University Medical Faculty, Izmir
- Residency
- Izmir Ataturk Teaching and Research Hospital
- Professorship
- Adnan Menderes University, 2011
- Founded
- First regenerative medicine department in a Turkish university
- Former roles
- Vice Dean, Medical Faculty, Adnan Menderes University; Head of Surgical Disciplines, Izmir University
- Current
- Founder, MEST Aesthetic Plastic Surgery Center, Izmir; Founder, G-CAT (Gene, Cell and Tissue) Academy, Istanbul
- Societies
- Member and National Delegate, ISPRES (International Society of Plastic and Regenerative Surgeons)
- Editorial
- Editor-in-Chief, Internet Journal of Plastic Surgery; editorial boards of several international journals
- Publications
- More than 70 peer-reviewed articles in international journals
- Techniques developed
- MEST (Mechanical Stromal-cell Transfer), ARAT (Adjustable Regenerative Adipose-tissue Transfer), Supercharged MEST
Core competencies
What the company is built to do
- Source-cell assessment
- Glutathione-based selection of producer-cell populations using the FreSHtracer platform, before any production run begins.
- Clean EV manufacture
- Phenol red-free, animal component-free culture and a controlled multi-step isolation and purification workflow.
- Recombinant protein production
- Sequence-defined human protein expression in a controlled microbial system, without human producer cells.
- Characterization & release
- Identity, purity, composition, potency and stability testing organized as a published per-lot record.
Two pathways. One standard.